---
description: Get a quick and detailed side-by-side comparison for MailCleaner vs Microsoft Defender for Office 365. GetApp will help you learn more about each of these software benefits and disadvantages.
image: https://gdm-localsites-assets-gfprod.imgix.net/images/getapp/og_logo-94fd2a03a6c7a0e54fc0c9e21a1c0ce9.png
title: MailCleaner vs Microsoft Defender for Office 365 Comparison | GetApp Australia 2026
---

Breadcrumb: [Home](/) > [Anti-spam Software](/directory/1019/anti-spam/software) > [MailCleaner \<span\>vs\</span\> Microsoft Defender for Office 365](https://www.getapp.com.au/compare/111737/2054932/mailcleaner/vs/microsoft-defender-for-office-365)

# Compare MailCleaner vs Microsoft Defender for Office 365

Canonical: https://www.getapp.com.au/compare/111737/2054932/mailcleaner/vs/microsoft-defender-for-office-365

> Detailed comparison between MailCleaner and Microsoft Defender for Office 365. Check ratings, reviews, pricing, and features to make the best decision for your business.

-----

## At a Glance

| Metric | MailCleaner | Microsoft Defender for Office 365 |
| **Overall rating** | 4.6/5 | 4.6/5 |
| **Total Reviews** | 26 | 235 |
| **Starting Price** | USD 130.00 | - |
| **Free Trial** | Yes | No |
| **Free Version** | Yes | - |
| **Deployment** | Cloud, SaaS, Web-based, Linux (Desktop), Windows (On-Premise), Linux (On-Premise) | Cloud, SaaS, Web-based |
| **Support** | Email/Help Desk, FAQs/Forum, Knowledge Base, Phone Support, 24/7 (Live rep), Chat | - |
| **Training** | In Person, Live Online, Webinars, Documentation, Videos | Live Online, Webinars, Documentation, Videos |

## Key features

### MailCleaner

- Allow/Block List
- Anti Spam
- Anti Virus
- Archiving & Retention
- Authentication
- Email Routing
- Encryption
- Filtering
- Reporting/Analytics
- Spam Blocker
- Spam Detection
- Spam Quarantine

### Microsoft Defender for Office 365

- Access Controls/Permissions
- Alerts/Escalation
- Allow/Block List
- Anti Spam
- Data Loss Prevention Software
- Email Attachment Protection
- Email Filtering
- Email Routing
- Filtering
- Greylisting
- Microsoft Outlook Integration
- Phishing Protection
- Reporting/Analytics
- Spam Blocker
- Spam Detection
- Spam Quarantine

## Links

- [View MailCleaner Profile](https://www.getapp.com.au/software/111737/mailcleaner)
- [View Microsoft Defender for Office 365 Profile](https://www.getapp.com.au/software/2054932/microsoft-defender-for-office-365)
- [View Original Comparison](https://www.getapp.com.au/compare/111737/2054932/mailcleaner/vs/microsoft-defender-for-office-365)

-----

## Structured Data

<script type="application/ld+json">
  {"@context":"https://schema.org","@graph":[{"name":"MailCleaner vs Microsoft Defender for Office 365 Comparison | GetApp Australia 2026","description":"Get a quick and detailed side-by-side comparison for MailCleaner vs Microsoft Defender for Office 365. GetApp will help you learn more about each of these software benefits and disadvantages.","url":"https://www.getapp.com.au/compare/111737/2054932/mailcleaner/vs/microsoft-defender-for-office-365","about":[{"@id":"https://www.getapp.com.au/software/111737/mailcleaner#software"},{"@id":"https://www.getapp.com.au/software/2054932/microsoft-defender-for-office-365#software"}],"breadcrumb":{"@id":"https://www.getapp.com.au/compare/111737/2054932/mailcleaner/vs/microsoft-defender-for-office-365#breadcrumblist"},"@id":"https://www.getapp.com.au/compare/111737/2054932/mailcleaner/vs/microsoft-defender-for-office-365#webpage","@type":["WebPage","CollectionPage"],"isPartOf":{"@id":"https://www.getapp.com.au/#website"},"inLanguage":"en-AU","publisher":{"@id":"https://www.getapp.com.au/#organization"}},{"name":"MailCleaner","description":"MailCleaner provides cloud and on-premise anti spam server protection for ISP SME SMI and large companies, as well as educational organisations and governments. \n\nMailCleaner uses a variety of filter layers, artificial intelligence algorithms, and frequent updates to analyze incoming email messages before forwarding “clean” messages to the user's original mail server, and placing messages infected with a virus or detected as spam, in quarantine. The delivery of quarantined messages can be manually forced by administrators, if required. \n\nMailCleaner offers users a simple way to review their quarantine lists, change their preferences, and, for users who have more than one e-mail address, consolidate reports.","image":"https://gdm-catalog-fmapi-prod.imgix.net/ProductScreenshot/da22390e-e893-4f27-9ee4-bc9445f90ac8.png","url":"https://www.getapp.com.au/software/111737/mailcleaner","@id":"https://www.getapp.com.au/software/111737/mailcleaner#software","@type":"SoftwareApplication","publisher":{"@id":"https://www.getapp.com.au/#organization"},"applicationCategory":"BusinessApplication","aggregateRating":{"@type":"AggregateRating","ratingValue":4.6,"bestRating":5,"ratingCount":26},"offers":{"price":"130","@type":"Offer","priceCurrency":"USD"},"operatingSystem":"Cloud, Linux, Windows on premise, Linux on premise"},{"name":"Microsoft Defender for Office 365","description":"Microsoft Defender for Office 365 is a cloud-based email security software designed to help businesses automatically detect, investigate, and resolve potential email threats on a centralized platform. Supervisors can configure security policies, perform spoof checks, and maintain a record of reported incidents. \n\nMicrosoft Defender for Office 365 allows organizations to monitor all incoming and outgoing emails, verify the authenticity of senders or domains, and scan email attachments to prevent malware attacks. Managers can view quarantined messages and monitor the impact of campaigns through actionable analytics. It also lets users filter metadata based on various options and receive automated alerts about unusual URL clicks or other suspicious activities. \n\nMicrosoft Defender for Office 365 enables businesses to automatically block spam messages and determine email traffic patterns using artificial intelligence (AI) technology and machine learning capabilities. The software also helps users offer prioritized protection to specific accounts and create custom queries to inspect security events.","image":"https://gdm-catalog-fmapi-prod.imgix.net/ProductScreenshot/d9d25d06-dd5f-467f-be05-1b51f5b10566.png","url":"https://www.getapp.com.au/software/2054932/microsoft-defender-for-office-365","@id":"https://www.getapp.com.au/software/2054932/microsoft-defender-for-office-365#software","@type":"SoftwareApplication","publisher":{"@id":"https://www.getapp.com.au/#organization"},"applicationCategory":"BusinessApplication","aggregateRating":{"@type":"AggregateRating","ratingValue":4.6,"bestRating":5,"ratingCount":235},"operatingSystem":"Cloud"},{"@id":"https://www.getapp.com.au/compare/111737/2054932/mailcleaner/vs/microsoft-defender-for-office-365#breadcrumblist","@type":"BreadcrumbList","itemListElement":[{"name":"Home","position":1,"item":"/","@type":"ListItem"},{"name":"Anti-spam Software","position":2,"item":"/directory/1019/anti-spam/software","@type":"ListItem"},{"name":"MailCleaner vs Microsoft Defender for Office 365","position":3,"item":"https://www.getapp.com.au/compare/111737/2054932/mailcleaner/vs/microsoft-defender-for-office-365","@type":"ListItem"}]}]}
</script>